Common Celebrex Side Effects
Common Celebrex side effects may include
- stomach pain, indigestion, gas, or diarrhea
- swelling in the hands or feet
- headache;
- skin reactions or bruising
- numbness, tingling, or weakness in the muscles
- skin pain followed by a red or purple rash that spreads and causes blistering and peeling
A very serious allergic reaction is rare, but you should get medical help immediately if you notice any symptoms of a serious allergic reaction, including fever, a rash or hives, swollen lymph nodes, itching or swelling, severe dizziness, or trouble breathing.
Is Celebrex A Blood Thinner
No, Celebrex isnt a blood thinner. Blood thinners are drugs that are used to help prevent blood clots. Celebrex, on the other hand, is a type of drug called a nonsteroidal anti-inflammatory drug . NSAIDs are used to treat pain and inflammation .
Aspirin is a different NSAID thats also used in low doses as a blood thinner. NSAIDs like Celebrex can sometimes prolong bleeding time. But unlike aspirin, Celebrex doesnt have a blood thinning effect.
Who Should Not Take This Medication
Do not take this medication if you:
- are allergic to celecoxib or any ingredients of the medication
- are allergic to sulfonamides
- are breast-feeding or planning to breast-feed
- are in the third trimester of pregnancy
- are planning to have or recently have had heart surgery
- have an active stomach or intestinal ulcer or active gastrointestinal bleeding
- have bleeding in the brain
- have experienced asthma, hives, or allergic-type reactions after taking acetylsalicylic acid or other NSAIDs
- have high blood potassium levels
- have inflammatory bowel disease
- have severe, uncontrolled heart failure
- have severely decreased kidney function or kidney function that is getting worse
- have severely decreased liver function or active liver disease
- have high levels of potassium in your blood
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How Do Celebrex And Mobic Work
Celebrex and Mobic both work by inhibiting the enzymes that promote the release of substances in your body that produce pain and inflammation. The difference is that Celebrex only inhibits the enzyme cyclooxygenase-2 , and Mobic inhibits both COX-1 and COX-2.
The COX-1 enzyme protects the lining of your stomach from acid. By selectively inhibiting COX-2, Celebrex is less likely to cause stomach bleeding than Mobic.
Celebrex can be used to treat the following conditions:
- osteoarthritis
- juvenile rheumatoid arthritis in patients two years and older
- arthritis of the spine
- acute pain
Mobic is indicated to treat the following:
- osteoarthritis
Can I Take Celebrex If I Have A Sulfa Allergy
Not according to the manufacturer of Celebrex, but in practice, this can be a slightly gray area.
If you have sulfa allergy, youve had an allergic reaction to a medication that contains sulfonamide. Sulfonamide medications include trimethoprim/sulfamethoxazole , sulfasalazine , and dapsone. If you have a sulfa allergy, its possible that taking a different sulfonamide medication could also cause an allergic reaction. Celebrex contains a sulfonamide medication.
However, some research suggests that not every medication that contains a sulfonamide will trigger an allergic reaction in people with a sulfa allergy. So in some cases, your doctor might consider prescribing Celebrex. But the decision would be made on a case-by-case basis.
If you have a sulfa allergy, you should talk with your doctor before taking Celebrex.
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Celebrex For Ankylosing Spondylitis
Celebrex is FDA-approved to treat ankylosing spondylitis in adults.
AS is a type of arthritis where there is bone fusion in the spine. AS mainly affects the lower part of the spine, where it joins the pelvis. But AS can also affect parts of the body, such as the shoulders, hips, ribs, heels, hands, and feet. The condition runs in families but is more common in young men.
With AS, you have inflammation in your spinal joints. The inflammation can damage the joints and cause new bone to form. Over time, the new bone growth can fuse the vertebrae together. AS can cause pain and stiffness that typically starts in the lower back and buttocks. Many people with AS also have other symptoms such as fatigue, bowel inflammation, and eye inflammation.
Effectiveness for ankylosing spondylitis
Celebrex is a commonly used NSAID thats well accepted as an effective treatment for AS. It reduces pain and stiffness, helping to improve daily functioning in people with this condition. The American College of Rheumatology recommends NSAIDs such as Celebrex for treating AS.
What Other Drugs Will Affect Celebrex
Ask your doctor before using Celebrex if you take an antidepressant, steroid medicine, or medicine to treat or prevent blood clots. Taking certain medicines with an NSAID may increase your risk of a stomach ulcer or bleeding.
Many drugs can interact with celecoxib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
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What Should I Discuss With My Healthcare Provider Before Taking Amlodipine And Celecoxib
Celecoxib can increase your risk of fatal heart attack or stroke, even if you don’t have any risk factors. Do not use this medicine just before or after heart bypass surgery .
Celecoxib may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using amlodipine and celecoxib, especially in older adults.
You should not use this medicine if you are allergic to amlodipine or celecoxib , or if you have:
- an allergy to sulfa drugs; or
- a history of asthma attack or severe allergic reaction after taking aspirin or an NSAID.
Tell your doctor if you have ever had:
- a stomach ulcer, bleeding in your stomach or intestines;
- bleeding problems;
- heart problems, coronary artery disease;
- liver or kidney disease; or
- if you smoke or drink alcohol.
If you are pregnant, you should not take celecoxib unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.
This medicine may affect fertility in women. Ask your doctor about this risk.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
What Is Aleve What Is Celebrex Are They The Same
Celebrex, brand name celecoxib, is a nonsteroidal anti-inflammatory drug used for the treatment of arthritis, pain, menstrual cramps, and colon polyps. Prostaglandins are chemicals that contribute to arthritis pain, fever, swelling, and tenderness caused by inflammation. Celebrex blocks the enzyme that makes prostaglandins , which results in lower concentrations of prostaglandins. Consequently, inflammation, pain, fever, swelling, and tenderness are reduced. Celebrex is different from other NSAIDs in that it causes less inflammation, and stomach and intestinal ulcers , and does not interfere with blood clotting.
Aleve is a nonsteroidal anti-inflammatory drug . Other NSAIDs include ibuprofen , indomethacin , nabumetone and others. These drugs are used for the management of mild to moderate pain, fever, and inflammation.
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This Prescription Drug Works No Better Than Cheaper Over
Q. Should I ask my doctor for Celebrex?
A. In most cases, nofor several reasons. First, the drug, which in generic form is known as celecoxib, doesnt ease pain from osteoarthritis better than related drugs available without a prescription, including ibuprofen and naproxen , according to our Best Buy Drugs analysis. And though some research suggests that celecoxib is less likely to cause stomach bleeding, it might be more likely than naproxen to increase the risk of heart attacks and strokes.
In addition, though celecoxib should be available next year as a generic and will eventually cost less than the brand-name original, it can take a year or more for savings to trickle down to consumers. We estimate that a year after it becomes available as a generic, celecoxib will cost about $70 per month. Thats roughly half of what brand-name Celebrex now costsbut about seven times as much as what generic ibuprofen or naproxen costs.
When To Stop The Drug And Get Immediate Medical Attention
- If signs of allergy occur, such as rapid breathing, gasping, wheezing, hives, skin rashes, puffy eyelids, and/or rapid heart beat occur.
- If you develop vision abnormalities.
- If you develop dizziness, depression, or confusion.
- If you develop yellowing of the eyes that could indicate liver injury .
- If your urine becomes cloudy or bloody, the amount of urine you pass suddenly decreases, or you develop new ankle swelling, all of which could indicate kidney problems. This is especially important to watch for if your kidney function has been noted, on lab testing, to have been abnormal in the past.
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How Do Prescription Discount Cards Work
Prescription discount cards, or;prescription savings cards, help you obtain the;lowest prescription price;for your medication. If your insurance does not cover your medication or the cost is too high on insurance, a free Rx savings card may save you up to 80% or more off the retail price. You can use the;ScriptSave® WellRx;discount card for the best prescription savings at a pharmacy near you.
Rosanna Sutherby is a freelance medical writer who has been a practicing pharmacist in her community for close to 20 years. She obtained her Doctor of Pharmacy from Nova Southeastern University in Ft. Lauderdale, FL. She utilizes her clinical training in the pharmacy, where she helps patients manage disease states such as asthma, diabetes, heart disease, hypertension, and many others. Dr. Sutherby reviews and recommends drug regimens based on patients concurrent conditions and potential drug interactions.
How Should I Use This Medication
The amount of celecoxib and how long it is taken varies according to the condition being treated. It should be used at the lowest dose possible for the shortest possible length of time to achieve pain relief.
Osteoarthritis: The usual recommended daily dose is 200;mg taken as a single dose or as 100;mg twice daily.
Ankylosing spondylitis: The usual recommended daily dose is 200;mg taken as a single dose or as 100;mg twice daily.
Rheumatoid arthritis: The usual recommended starting dose is 100;mg twice daily. This may be increased to 200;mg twice daily as directed by your doctor.
Moderate-to-severe pain: The usual recommended dose is 400;mg as a single dose on the first day, followed by 200;mg once daily. Treatment should not exceed 7 days. The maximum recommended dose is 400;mg a day.
Celecoxib may be taken with or without food.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Store this medication at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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What Are The Side Effects Of Celebrex
Get emergency medical help if you have signs of an allergic reaction or a severe skin reaction .
Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.
Stop using celecoxib and call your doctor at once if you have:
- the first sign of any skin rash, no matter how mild;
- heart problems–swelling, rapid weight gain, feeling short of breath;
- signs of stomach bleeding–bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
- liver problems–nausea, stomach pain , itching, tiredness, dark urine, jaundice ;
- kidney problems–little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or
- low red blood cells –pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.
Common side effects may include:
- stomach pain, heartburn, gas, diarrhea, constipation, nausea, vomiting;
- swelling in your hands or feet;
- dizziness; or
- cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Celebrex For Juvenile Rheumatoid Arthritis
Celebrex is FDA-approved to treat juvenile rheumatoid arthritis in children ages 2 years and older.
JRA is also called juvenile idiopathic arthritis. Idiopathic means that the cause isnt fully understood. Like adult RA, JRA appears to develop when a childs immune system mistakenly attacks their joints. But JRA isnt simply a child version of the adult condition.
JRA can affect one or many joints, causing pain, swelling, and stiffness. But children with this condition can also have other symptoms, such as eye inflammation, fatigue, fever, swollen glands, and a rash.
Effectiveness for juvenile rheumatoid arthritis
Celebrex is a commonly used NSAID thats well accepted as an effective treatment for JRA. The drug helps reduce joint pain and stiffness, helping to improve daily functioning in children with this condition. NSAIDs such as Celebrex are recommended in guidelines for treating JRA from the American College of Rheumatology.
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What Are The Possible Side Effects Of Amlodipine And Celecoxib
Get emergency medical help if you have signs of an allergic reaction or a severe skin reaction .
Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.
Stop using this medicine and call your doctor at once if you have:
- nausea, weakness, tingly feeling;
- new or worsening chest pain;
- the first sign of any skin rash, no matter how mild;
- rapid weight gain, feeling short of breath;
- swelling in your arms, hands, legs, or feet;
- signs of stomach bleeding –bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
- liver problems –stomach pain , dark urine, jaundice ; or
- low red blood cells –pale skin, unusual tiredness, feeling light-headed, cold hands and feet.
Common side effects may include:
- stomach pain, heartburn, gas, diarrhea, nausea;
- drowsiness, feeling tired;
- flushing ;
- headache, dizziness; or
- cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings For Other Groups
For pregnant women: This drug falls into one of two pregnancy categories, depending on how far along you are in your pregnancy. For your first 30 weeks of pregnancy, its a category C pregnancy drug. This category means two things:
- Research in animals has shown adverse effects to the fetus when the mother takes the drug.
- There havent been enough studies done in humans to be certain how the drug might affect the fetus.
-
After 30 weeks of pregnancy, this drug is a category D pregnancy drug. For this category:
- Studies show a risk of adverse effects to the fetus when the mother takes the drug.
- The benefits of taking the drug during pregnancy may outweigh the potential risks in certain cases.
-
Tell your doctor if youre pregnant or plan to become pregnant. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
For women who are breastfeeding: This drug has been shown to pass through breast milk. You and your doctor should decide if youll take this drug or breastfeed.
For seniors: This drug has been studied in a small number of people older than 65 years. If youre 65 years or older, you may have increased risk of stomach problems and kidney failure that may be fatal.
For children: This drug hasnt been studied in people younger than 2 years.
This dosage information is for celecoxib oral capsule. All possible dosages and forms may not be included here. Your dose, form, and how often you take it will depend on:
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Dosage And Intake Instructions
You should use this drug as is prescribed by your doctor or follow the description mentioned on the label of the drugs. Do not exceed dosage recommended or prescribed by your physician or pharmacist. ;
The maximum amount of dose allowed is 800 mg per dose or 3200 mg per day. Do not cross this daily limit of ibuprofen .
Avoid self-medication in the case of children. Follow the dosing schedule as prescribed by the doctor.
Use of ibuprofen with milk decreases the gastrointestinal side effects of this drug.
If youre using a suspension, shake it well before using.
Is Celebrex Or Ibuprofen Better
Both drugs can be very effective in treating arthritis as well as other conditions. Depending on what condition you are treating, and taking into account any other medical conditions and risk factors you have, as well as other medications you are taking, your doctor can help recommend the appropriate medication for you.
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Celebrex Stomach Ulcers And Gastrointestinal Bleeding
When you take a prescription drug, you expect it to do one thing: alleviate your symptoms. While we all understand that all drugs have side effects, that does not mean that we intend to put our health in danger. We place our trust in the medical professionals to prescribe us the medicines needed to bring us back to health; unfortunately some drugs are misleading, even to physicians. Celebrex came out in 1999 as one of a new classification of non-steroidal anti-inflammatory drugs , called COX-2 inhibitors. It relieves pain for those suffering from arthritis by combating inflammation caused by the natural enzyme COX-2.
Unfortunately, sometimes drugs go on the market without adequate testing and research first, and sometimes side effects emerge that were not part of the original bargain. That was the case with Celebrex. When it became available in 1999, Celebrex was indeed cause to celebrate. It alleviated arthritis pain and other types of pain , and appeared to have minimal side effects. It even sidestepped the common gastrointestinal problems that other NSAIDs caused, because it did not interfere with COX-1, which protects the lining of the stomach.
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